How are infectious diseases caught?
How disease is caught and understanding pathogens and their spread?
Learning outcomes & key terms
Innovation and equal access, inspiration for all
- To understand in depth four pathogens that cause disease
- Understand how disease spreads
- Understand how disease infects
Any condition that impairs the normal functioning of the body. Occurs when homeostasis can’t be achieved. It is a disruption of normal body functions and homeostasis.
Non-infectious/non-communicable disease: a medical condition or disease that is non-infectious. They can be chronic and progress slowly or result in rapid decline and death. includes most cancers, diabetes, hypertension, rheumatoid arthritis, and sickle cell anaemia.
Infectious/communicable disease: an illness resulting from an infection. It is a disease caused by a pathogen (also known as a germ). Examples include HIV, Ebola, chicken pox, the common cold, hepatitis, influenza, Lyme disease, meningitis, strep throat, tetanus, tuberculosis, Zika virus, and many others.
To transmit an infectious disease
The invasion of an organism’s body tissues by disease-causing agents, their multiplication, and the reaction of the host tissues to these organisms and the toxins they produce.
Common ways to become infected
Through person-to-person physical contact, inhaling a pathogen, eating/drinking contaminated foods, contact with an animal carrying the pathogen, insect bites.
An organism capable of causing disease.
Examples of pathogens
Bacteria, viruses, fungi, parasitic worms.
Describing how the requirements for life (for example oxygen, nutrients, water and removal of waste) are provided through the coordinated function of body systems such as the respiratory, circulatory, digestive, nervous and excretory systems.
Explaining how body systems work together to maintain a functioning body using models, flow diagrams or simulations.
Investigating the response of the body to changes as a result of the presence of micro-organisms.
Science as a human endeavour
Scientific understanding, including models and theories, is contestable and is refined over time through a process of review by the scientific community.
Advances in scientific understanding often rely on technological advances and are often linked to scientific discoveries.
People use scientific knowledge to evaluate whether they accept claims, explanations or predictions, and advances in science can affect people’s lives, including generating new career opportunities.
Values and needs of contemporary society can influence the focus of scientific research.
Science enquiry skills
Formulate questions or hypotheses that can be investigated scientifically.
Analyse patterns and trends in data, including describing relationships between variables and identifying inconsistencies.
What causes disease?
Disease is caused by some germs, called pathogens
We are going to look at four main classes of pathogens
Bacteria are living cells that are microscopic in size
They can range from 5 to 20 micrometers in size
A micrometer is a millionth of a metre
Not all bacteria are bad e.g. some bacteria has been used for years (centuries even) for the production of cheese and yoghurt
Pathogenic bacteria include Cholera, Salmonella, Tuberculosis and E.Coli
Once these pathogenic bacteria get inside our body they may release chemicals called toxins. These toxins and our body’s response to them can make us feel sick
Bacteria Cell Structure
Bacteria Cells are simple with four main parts:
- Cell Wall: Helps maintain shape and prevents bursting
- Bacterial DNA: Controls the division of the cell and how the cell functions
- Plasmid DNA: Small pieces of extra DNA, circular in shape that jumps between bacteria
- Flagellum: Helps bacteria move, not essential
Types of Bacteria
There are three main types of bacteria cells, scientists use this characteristic to help identify infections
- Coccus (Spherical)
- Bacillus (Rod)
- Spirochete (Spiral)
Viruses are much smaller than bacteria, they are not living and can only survive inside another cell
Viruses attack specific cells – the flu virus targets and attacks cells in the respiratory system (throat and lungs)
Once the virus infects a cell it starts to replicate until it fills the cells and causes the cell to burst
Examples of viruses include: SARS-CoV2, measles, mumps, rubella, influenza, chickenpox and polio
Structure of a Virus
A virus has a simple structure:
- RNA or DNA: the grey genetic material is what the virus needs to take over the cell it is infecting – found on the inside of viruses
- Protein Coat to attach and penetrate cells: the S (spike) protein is used by SARS CoV2, the cause of COVID-19
Fungi can often be seen with the naked eye. Mould and Athlete’s Foot are examples of fungal infections
One of the most well known forms of fungus is yeast
Yeast is a single celled fungus that is used to ferment beer and cause bread to rise
Yeast can also cause infection
Structure of Yeast
There are different types of yeast but their cells have similar structures:
1. Nucleus: contains genetic material which controls the replication of the cell
2. Cytoplasm: where chemical reactions of the cell take place
3. Cell Wall: keeps the shape of the cell
4. Bud: new yeast cell
Not everything that carries a disease is a micro-organism
A parasite is an organism that lives in or on another organism – the other organism is called the host
Parasites can include head-lice, fleas and tapeworms – they can live inside or outside the body
Case Study Campylobacter jejuni infection
You’ve just had a bad case of food poisoning
You’ve been infected with Campylobacter jejuni which is a type of bacterium
Symptoms appear within 1-5 days
Campylobacter jejuni is the most common cause of food poisoning and is often found on raw chicken
Bacterial cells can multiply every 20 minutes. So if you start with 2 cells, in 20 minutes you will have 4, after 40 minutes you will have 8, after 60 minutes, 16 cells and so on
So, if you ate the chicken at 7pm and ingested 2 bacteria cells at what time will you have over 250 cells?
The infective dose can be as few as 1 or 2 bacteria
- There four pathogens that cause disease; Bacteria, Fungi, Viruses, Parasites
- Disease can spread through direct or indirect contact, insect bites and food contamination
- Through good hygiene we can remove a lot of the risk of the spread of pathogens
- Disease can spread very quickly. Bacteria cells can multiply every 20 minutes
1) The four main classes of pathogen are
a) Bacteria, viruses, fungi, prions
b) Bacteria, viruses, fungi, parasites
c) Bacteria, viruses, fungi, prokaryotes
d) Bacteria, viruses, fungi, eukaryotes
2) Types of bacteria are
a) Coccus (spherical)
b) Bacillus (rod)
c) Spirochete (spiral)
d) All of the above
3) A virus has
a) A nucleus
d) Genetic material and a protein coat
4) Pathogens can spread by
a) Insect bites
b) Food contamination
c) Coughing and sneezing
d) All of the above